2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile structure

2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile

TL;DR: 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile (CAS 338773-91-4) is a chemical compound with molecular formula C14H12F2N4 and molecular weight 274.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(2,4-difluoroanilino)-4-(dimethylamino)pyridine-3-carbonitrile

Also Known As: 2-(2,4-difluoroanilino)-4-(dimethylamino)nicotinonitrile, 2K-101, 2-(2,4-difluoroanilino)-4-(dimethylamino)pyridine-3-carbonitrile, 2-[(2,4-difluorophenyl)amino]-4-(dimethylamino)pyridine-3-carbonitrile, 2-[(2,4-difluorophenyl)amino]-4-dimethylamino-pyridine-3-carbonitrile

CAS: 338773-91-4
Molecular Formula C14H12F2N4
Molecular Weight 274.10 g/mol
LogP 3.04108
Topological Polar Surface Area 51.95 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 274.103
Heavy Atoms 20
Complexity 677.3595

Chemical Identifiers

CAS Number 338773-91-4
SMILES CN(C)C1=C(C(=NC=C1)NC2=C(C=C(C=C2)F)F)C#N

Product Overview

2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile (CAS 338773-91-4), with molecular formula C14H12F2N4 and molecular weight 274.10 g/mol. IUPAC: 2-(2,4-difluoroanilino)-4-(dimethylamino)pyridine-3-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile

XLogP
3.04108
TPSA (Topological Polar Surface Area)
51.95
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
20
Complexity
677.3595
Exact Mass
274.103
Monoisotopic Mass
274.103
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile

The XLogP value of 3.04108 indicates that 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.95 Ų, 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile?

The CAS number of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile is 338773-91-4.

What is the molecular formula of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile?

The molecular formula of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile is C14H12F2N4.

What is the molecular weight of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile?

The molecular weight of 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile is 274.10 g/mol.

Where can I buy 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile?

You can request a quote for 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile?

Yes, KEHONG BIO provides custom synthesis services for 2-(2,4-Difluoroanilino)-4-(dimethylamino)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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