8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine
TL;DR: 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine (CAS 338773-34-5) is a chemical compound with molecular formula C7H4ClF3N4 and molecular weight 236.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine
Also Known As: 8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine, 8-chloro-6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridin-3-amine, 3998AB, 3-Amino-8-chloro-6-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyridine, 8-Chloro-6-(trifluoromethyl)[1,2,4]triazolo-[4,3-a]pyridin-3-amine
| Molecular Formula | C7H4ClF3N4 |
|---|---|
| Molecular Weight | 236.01 g/mol |
| LogP | 1.9837 |
| Topological Polar Surface Area | 56.21 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 236.00766 |
| Heavy Atoms | 15 |
| Complexity | 518.66504 |
Chemical Identifiers
| CAS Number | 338773-34-5 |
|---|---|
| SMILES | C1=C(C2=NN=C(N2C=C1C(F)(F)F)N)Cl |
Product Overview
8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine (CAS 338773-34-5), with molecular formula C7H4ClF3N4 and molecular weight 236.01 g/mol. IUPAC: 8-chloro-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-amine.
Chemical Property Profile of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine
Property Insights of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine
The XLogP value of 1.9837 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine. With a topological polar surface area (TPSA) of 56.21 Ų, 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine?
The CAS number of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine is 338773-34-5.
What is the molecular formula of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine?
The molecular formula of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine is C7H4ClF3N4.
What is the molecular weight of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine?
The molecular weight of 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine is 236.01 g/mol.
Where can I buy 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine?
You can request a quote for 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine?
Yes, KEHONG BIO provides custom synthesis services for 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo(4,3-a)pyridin-3-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.