![5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide structure](/static/products/3387/338770-41-5.webp)
5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide
TL;DR: 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide (CAS 338770-41-5) is a chemical compound with molecular formula C18H18ClF3N4OS and molecular weight 430.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)ethenyl]-N-(dimethylaminomethylidene)thiophene-2-carboxamide
Also Known As: 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide, 5-[1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-(dimethylamino)ethenyl]-N-(dimethylaminomethylidene)thiophene-2-carboxamide
| Molecular Formula | C18H18ClF3N4OS |
|---|---|
| Molecular Weight | 430.08 g/mol |
| LogP | 4.4962 |
| Topological Polar Surface Area | 48.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 430.0842 |
| Heavy Atoms | 28 |
| Complexity | 919.7948 |
Chemical Identifiers
| CAS Number | 338770-41-5 |
|---|---|
| SMILES | CN(C)C=C(C1=CC=C(S1)C(=O)N=CN(C)C)C2=C(C=C(C=N2)C(F)(F)F)Cl |
Product Overview
5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide (CAS 338770-41-5), with molecular formula C18H18ClF3N4OS and molecular weight 430.08 g/mol. IUPAC: 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)ethenyl]-N-(dimethylaminomethylidene)thiophene-2-carboxamide.
Chemical Property Profile of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide
Property Insights of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide
The XLogP value of 4.4962 indicates that 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.8 Ų, 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide?
The CAS number of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide is 338770-41-5.
What is the molecular formula of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide?
The molecular formula of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide is C18H18ClF3N4OS.
What is the molecular weight of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide?
The molecular weight of 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide is 430.08 g/mol.
Where can I buy 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide?
You can request a quote for 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-[1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-(dimethylamino)vinyl]-N-[(dimethylamino)methylene]-2-thiophenecarboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.