N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine
TL;DR: N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine (CAS 338754-31-7) is a chemical compound with molecular formula C16H11F3N4 and molecular weight 316.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-phenyl-2-pyridin-2-yl-6-(trifluoromethyl)pyrimidin-4-amine
Also Known As: Bionet2_000138, N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine, N-phenyl-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine, N-phenyl-2-pyridin-2-yl-6-(trifluoromethyl)pyrimidin-4-amine, N-phenyl-2-(2-pyridyl)-6-(trifluoromethyl)pyrimidin-4-amine
| Molecular Formula | C16H11F3N4 |
|---|---|
| Molecular Weight | 316.09 g/mol |
| LogP | 4.301 |
| Topological Polar Surface Area | 50.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 316.09357 |
| Heavy Atoms | 23 |
| Complexity | 789.42566 |
Chemical Identifiers
| CAS Number | 338754-31-7 |
|---|---|
| SMILES | C1=CC=C(C=C1)NC2=NC(=NC(=C2)C(F)(F)F)C3=CC=CC=N3 |
Product Overview
N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine (CAS 338754-31-7), with molecular formula C16H11F3N4 and molecular weight 316.09 g/mol. IUPAC: N-phenyl-2-pyridin-2-yl-6-(trifluoromethyl)pyrimidin-4-amine.
Chemical Property Profile of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine
Property Insights of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine
The XLogP value of 4.301 indicates that N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.7 Ų, N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine?
The CAS number of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine is 338754-31-7.
What is the molecular formula of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine?
The molecular formula of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine is C16H11F3N4.
What is the molecular weight of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine?
The molecular weight of N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine is 316.09 g/mol.
Where can I buy N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine?
You can request a quote for N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for N-phenyl-2-(2-pyridinyl)-6-(trifluoromethyl)-4-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.