Glyburide mixture with Metformin hydrochloride structure

Glyburide mixture with Metformin hydrochloride

TL;DR: Glyburide mixture with Metformin hydrochloride (CAS 338752-31-1) is a chemical compound with molecular formula C27H40Cl2N8O5S and molecular weight 658.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide;3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride

Also Known As: Glucovance, Glyburide-metformin, Glyburide mixture with metformin, Glyburide and metformin hydrochloride, Glyburide mixture with Metformin HCl

CAS: 338752-31-1
Molecular Formula C27H40Cl2N8O5S
Molecular Weight 658.22 g/mol
LogP 2.81967
Topological Polar Surface Area 213.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 6
Rotatable Bonds 10
Exact Mass 658.2219
Heavy Atoms 43
Complexity 878.0

Chemical Identifiers

CAS Number 338752-31-1
SMILES CN(C)C(=N)N=C(N)N.COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3.Cl
InChIKey HCEQQASHRRPQFE-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (4 patents)

Product Overview

Glyburide mixture with Metformin hydrochloride (CAS 338752-31-1), with molecular formula C27H40Cl2N8O5S and molecular weight 658.22 g/mol. IUPAC: 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide;3-(diaminomethylidene)-1,1-dimethylguanidine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Glyburide mixture with Metformin hydrochloride

XLogP
2.81967
TPSA (Topological Polar Surface Area)
213.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
6
Rotatable Bonds
10
Heavy Atoms
43
Complexity
878.0
Exact Mass
658.2219
Monoisotopic Mass
658.2219
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Glyburide mixture with Metformin hydrochloride

The XLogP value of 2.81967 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Glyburide mixture with Metformin hydrochloride. The TPSA of 213.0 Ų indicates high polarity, suggesting Glyburide mixture with Metformin hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Glyburide mixture with Metformin hydrochloride has 7 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Glyburide mixture with Metformin hydrochloride?

The CAS number of Glyburide mixture with Metformin hydrochloride is 338752-31-1.

What is the molecular formula of Glyburide mixture with Metformin hydrochloride?

The molecular formula of Glyburide mixture with Metformin hydrochloride is C27H40Cl2N8O5S.

What is the molecular weight of Glyburide mixture with Metformin hydrochloride?

The molecular weight of Glyburide mixture with Metformin hydrochloride is 658.22 g/mol.

Where can I buy Glyburide mixture with Metformin hydrochloride?

You can request a quote for Glyburide mixture with Metformin hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Glyburide mixture with Metformin hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Glyburide mixture with Metformin hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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