![N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine structure](/static/products/3384/338409-42-0.webp)
N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine
TL;DR: N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine (CAS 338409-42-0) is a chemical compound with molecular formula C13H13ClF3N3S and molecular weight 335.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-tert-butyl-N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1,3-thiazol-2-amine
Also Known As: N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine, N-(4-tert-butyl-1,3-thiazol-2-yl)-3-chloro-5-(trifluoromethyl)pyridin-2-amine, 4-tert-butyl-N-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1,3-thiazol-2-amine, 4-tert-butyl-N-[3-chloro-5-(trifluoromethyl)-2-pyridyl]thiazol-2-amine, N-[4-(t-Butyl)-1,3-thiaZol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine
| Molecular Formula | C13H13ClF3N3S |
|---|---|
| Molecular Weight | 335.05 g/mol |
| LogP | 5.2514 |
| Topological Polar Surface Area | 37.81 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 335.0471 |
| Heavy Atoms | 21 |
| Complexity | 646.84155 |
Chemical Identifiers
| CAS Number | 338409-42-0 |
|---|---|
| SMILES | CC(C)(C)C1=CSC(=N1)NC2=C(C=C(C=N2)C(F)(F)F)Cl |
Product Overview
N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine (CAS 338409-42-0), with molecular formula C13H13ClF3N3S and molecular weight 335.05 g/mol. IUPAC: 4-tert-butyl-N-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-1,3-thiazol-2-amine.
Chemical Property Profile of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine
Property Insights of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine
The XLogP value of 5.2514 indicates that N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.81 Ų, N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine?
The CAS number of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine is 338409-42-0.
What is the molecular formula of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine?
The molecular formula of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine is C13H13ClF3N3S.
What is the molecular weight of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine?
The molecular weight of N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine is 335.05 g/mol.
Where can I buy N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine?
You can request a quote for N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine?
Yes, KEHONG BIO provides custom synthesis services for N-[4-(tert-butyl)-1,3-thiazol-2-yl]-3-chloro-5-(trifluoromethyl)-2-pyridinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.