2H-912 structure

2H-912

TL;DR: 2H-912 (CAS 338399-22-7) is a chemical compound with molecular formula C19H11Cl2F3N4O2 and molecular weight 454.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[(4-chlorophenyl)methyl]-3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-2,4-dioxopyrimidine-5-carbonitrile

Also Known As: 2H-912, 1-(4-chlorobenzyl)-3-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile, 1-[(4-chlorophenyl)methyl]-3-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]-2,4-dioxopyrimidine-5-carbonitrile, 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-1-[(4-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile

CAS: 338399-22-7
Molecular Formula C19H11Cl2F3N4O2
Molecular Weight 454.02 g/mol
LogP 3.69888
Topological Polar Surface Area 80.68 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 454.02112
Heavy Atoms 30
Complexity 1259.232

Chemical Identifiers

CAS Number 338399-22-7
SMILES C1=CC(=CC=C1CN2C=C(C(=O)N(C2=O)CC3=C(C=C(C=N3)C(F)(F)F)Cl)C#N)Cl

Product Overview

2H-912 (CAS 338399-22-7), with molecular formula C19H11Cl2F3N4O2 and molecular weight 454.02 g/mol. IUPAC: 1-[(4-chlorophenyl)methyl]-3-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-2,4-dioxopyrimidine-5-carbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2H-912

XLogP
3.69888
TPSA (Topological Polar Surface Area)
80.68
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
30
Complexity
1259.232
Exact Mass
454.02112
Monoisotopic Mass
454.02112
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2H-912

The XLogP value of 3.69888 indicates that 2H-912 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.68 Ų falls within the moderate polarity range, balancing permeability and solubility for 2H-912. Following Lipinski's Rule of Five, 2H-912 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2H-912?

The CAS number of 2H-912 is 338399-22-7.

What is the molecular formula of 2H-912?

The molecular formula of 2H-912 is C19H11Cl2F3N4O2.

What is the molecular weight of 2H-912?

The molecular weight of 2H-912 is 454.02 g/mol.

Where can I buy 2H-912?

You can request a quote for 2H-912 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2H-912?

Yes, KEHONG BIO provides custom synthesis services for 2H-912 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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