2G-318S
TL;DR: 2G-318S (CAS 338396-93-3) is a chemical compound with molecular formula C17H12F3N3OS and molecular weight 363.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-methyl-2-pyridin-4-yl-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
Also Known As: 2G-318S, 4-methyl-2-(pyridin-4-yl)-N-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide, 4-methyl-2-(pyridin-4-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide, 4-methyl-2-pyridin-4-yl-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide, 4-methyl-2-(4-pyridyl)-N-[3-(trifluoromethyl)phenyl]thiazole-5-carboxamide
| Molecular Formula | C17H12F3N3OS |
|---|---|
| Molecular Weight | 363.07 g/mol |
| LogP | 4.78462 |
| Topological Polar Surface Area | 54.88 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 363.0653 |
| Heavy Atoms | 25 |
| Complexity | 907.0016 |
Chemical Identifiers
| CAS Number | 338396-93-3 |
|---|---|
| SMILES | CC1=C(SC(=N1)C2=CC=NC=C2)C(=O)NC3=CC=CC(=C3)C(F)(F)F |
Product Overview
2G-318S (CAS 338396-93-3), with molecular formula C17H12F3N3OS and molecular weight 363.07 g/mol. IUPAC: 4-methyl-2-pyridin-4-yl-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide.
Chemical Property Profile of 2G-318S
Property Insights of 2G-318S
The XLogP value of 4.78462 indicates that 2G-318S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.88 Ų, 2G-318S exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2G-318S has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2G-318S?
The CAS number of 2G-318S is 338396-93-3.
What is the molecular formula of 2G-318S?
The molecular formula of 2G-318S is C17H12F3N3OS.
What is the molecular weight of 2G-318S?
The molecular weight of 2G-318S is 363.07 g/mol.
Where can I buy 2G-318S?
You can request a quote for 2G-318S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2G-318S?
Yes, KEHONG BIO provides custom synthesis services for 2G-318S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.