10K-354S
TL;DR: 10K-354S (CAS 337922-23-3) is a chemical compound with molecular formula C21H15ClF4N2O3S and molecular weight 486.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[N-(4-chlorophenyl)sulfonyl-3-(trifluoromethyl)anilino]-N-(2-fluorophenyl)acetamide
Also Known As: 10K-354S, 2-[[(4-chlorophenyl)sulfonyl]-3-(trifluoromethyl)anilino]-N-(2-fluorophenyl)acetamide, 2-[N-(4-chlorophenyl)sulfonyl-3-(trifluoromethyl)anilino]-N-(2-fluorophenyl)acetamide, N-(2-fluorophenyl)-2-{N-[3-(trifluoromethyl)phenyl]4-chlorobenzenesulfonamido}acetamide, N-(2-fluorophenyl)-2-{N-[3-(trifluoromethyl)phenyl]-4-chlorobenzenesulfonamido}acetamide
| Molecular Formula | C21H15ClF4N2O3S |
|---|---|
| Molecular Weight | 486.04 g/mol |
| LogP | 5.3319 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 486.04282 |
| Heavy Atoms | 32 |
| Complexity | 1232.2922 |
Chemical Identifiers
| CAS Number | 337922-23-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)NC(=O)CN(C2=CC=CC(=C2)C(F)(F)F)S(=O)(=O)C3=CC=C(C=C3)Cl)F |
Product Overview
10K-354S (CAS 337922-23-3), with molecular formula C21H15ClF4N2O3S and molecular weight 486.04 g/mol. IUPAC: 2-[N-(4-chlorophenyl)sulfonyl-3-(trifluoromethyl)anilino]-N-(2-fluorophenyl)acetamide.
Chemical Property Profile of 10K-354S
Property Insights of 10K-354S
The XLogP value of 5.3319 indicates that 10K-354S is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for 10K-354S. Following Lipinski's Rule of Five, 10K-354S has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10K-354S?
The CAS number of 10K-354S is 337922-23-3.
What is the molecular formula of 10K-354S?
The molecular formula of 10K-354S is C21H15ClF4N2O3S.
What is the molecular weight of 10K-354S?
The molecular weight of 10K-354S is 486.04 g/mol.
Where can I buy 10K-354S?
You can request a quote for 10K-354S directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10K-354S?
Yes, KEHONG BIO provides custom synthesis services for 10K-354S and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.