![4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine structure](/static/products/3379/337919-73-0.webp)
4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine
TL;DR: 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine (CAS 337919-73-0) is a chemical compound with molecular formula C20H18ClF3N6 and molecular weight 434.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[4-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]phenyl]pyrimidin-2-amine
Also Known As: 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine, 4-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)pyrimidin-2-amine, 4-[4-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]phenyl]pyrimidin-2-amine, 4-(4-{4-3-Chloro-5-(trifluoromethyl)-2-pyridinylpiperazino}phenyl)-2-pyrimidinamine, 4-[4-[4-[3-chloro-5-(trifluoromethyl)-2-pyridyl]piperazin-1-yl]phenyl]pyrimidin-2-amine
| Molecular Formula | C20H18ClF3N6 |
|---|---|
| Molecular Weight | 434.12 g/mol |
| LogP | 4.1196 |
| Topological Polar Surface Area | 71.17 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 434.12335 |
| Heavy Atoms | 30 |
| Complexity | 1033.4569 |
Chemical Identifiers
| CAS Number | 337919-73-0 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)C3=NC(=NC=C3)N)C4=C(C=C(C=N4)C(F)(F)F)Cl |
Product Overview
4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine (CAS 337919-73-0), with molecular formula C20H18ClF3N6 and molecular weight 434.12 g/mol. IUPAC: 4-[4-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]phenyl]pyrimidin-2-amine.
Chemical Property Profile of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine
Property Insights of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine
The XLogP value of 4.1196 indicates that 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.17 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine. Following Lipinski's Rule of Five, 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine?
The CAS number of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine is 337919-73-0.
What is the molecular formula of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine?
The molecular formula of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine is C20H18ClF3N6.
What is the molecular weight of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine?
The molecular weight of 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine is 434.12 g/mol.
Where can I buy 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine?
You can request a quote for 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}phenyl)-2-pyrimidinamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.