![1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid structure](/static/products/3379/337919-65-0.webp)
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid
TL;DR: 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid (CAS 337919-65-0) is a chemical compound with molecular formula C12H12ClF3N2O2 and molecular weight 308.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperidine-4-carboxylic acid
Also Known As: 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid, Bionet2_000205, 1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-piperidinecarboxylic acid, Pyridine,2,6-dibromo-4-phenyl, 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carboxylic acid
| Molecular Formula | C12H12ClF3N2O2 |
|---|---|
| Molecular Weight | 308.05 g/mol |
| LogP | 3.0548 |
| Topological Polar Surface Area | 53.43 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 308.05392 |
| Heavy Atoms | 20 |
| Complexity | 513.9142 |
Chemical Identifiers
| CAS Number | 337919-65-0 |
|---|---|
| SMILES | C1CN(CCC1C(=O)O)C2=C(C=C(C=N2)C(F)(F)F)Cl |
Product Overview
1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid (CAS 337919-65-0), with molecular formula C12H12ClF3N2O2 and molecular weight 308.05 g/mol. IUPAC: 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperidine-4-carboxylic acid.
Chemical Property Profile of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid
Property Insights of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid
The XLogP value of 3.0548 indicates that 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.43 Ų, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid?
The CAS number of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid is 337919-65-0.
What is the molecular formula of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid?
The molecular formula of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid is C12H12ClF3N2O2.
What is the molecular weight of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid?
The molecular weight of 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid is 308.05 g/mol.
Where can I buy 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid?
You can request a quote for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]piperidine-4-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.