Dexamethasone Valerate
TL;DR: Dexamethasone Valerate (CAS 33755-46-3) is a chemical compound with molecular formula C27H37FO6 and molecular weight 476.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
Also Known As: Dexamethasone valerate, Voalla ointment, Voalla, Zalucs, Dexamethasone 17-valerate
| Molecular Formula | C27H37FO6 |
|---|---|
| Molecular Weight | 476.26 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 101.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 476.25742 |
| Heavy Atoms | 34 |
| Complexity | 957.0 |
Chemical Identifiers
| CAS Number | 33755-46-3 |
|---|---|
| SMILES | CCCCC(=O)O[C@@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO |
| InChIKey | SNHRLVCMMWUAJD-OMPPIWKSSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Dexamethasone Valerate (CAS 33755-46-3), with molecular formula C27H37FO6 and molecular weight 476.26 g/mol. IUPAC: [(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate.
Chemical Property Profile of Dexamethasone Valerate
Property Insights of Dexamethasone Valerate
The XLogP value of 3.6 indicates that Dexamethasone Valerate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 101.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Dexamethasone Valerate. Following Lipinski's Rule of Five, Dexamethasone Valerate has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Dexamethasone Valerate?
The CAS number of Dexamethasone Valerate is 33755-46-3.
What is the molecular formula of Dexamethasone Valerate?
The molecular formula of Dexamethasone Valerate is C27H37FO6.
What is the molecular weight of Dexamethasone Valerate?
The molecular weight of Dexamethasone Valerate is 476.26 g/mol.
Where can I buy Dexamethasone Valerate?
You can request a quote for Dexamethasone Valerate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Dexamethasone Valerate?
Yes, KEHONG BIO provides custom synthesis services for Dexamethasone Valerate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.