4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one
TL;DR: 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one (CAS 337492-45-2) is a chemical compound with molecular formula C24H18N2O5 and molecular weight 414.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4Z)-4-[hydroxy(phenyl)methylidene]-1-(3-methylphenyl)-5-(2-nitrophenyl)pyrrolidine-2,3-dione
Also Known As: BIM-0012180.P001, 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one, (4Z)-4-[hydroxy(phenyl)methylidene]-1-(3-methylphenyl)-5-(2-nitrophenyl)pyrrolidine-2,3-dione
| Molecular Formula | C24H18N2O5 |
|---|---|
| Molecular Weight | 414.12 g/mol |
| LogP | 4.52952 |
| Topological Polar Surface Area | 100.75 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 414.12158 |
| Heavy Atoms | 31 |
| Complexity | 1233.4818 |
Chemical Identifiers
| CAS Number | 337492-45-2 |
|---|---|
| SMILES | CC1=CC(=CC=C1)N2C(/C(=C(\C3=CC=CC=C3)/O)/C(=O)C2=O)C4=CC=CC=C4[N+](=O)[O-] |
Product Overview
4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one (CAS 337492-45-2), with molecular formula C24H18N2O5 and molecular weight 414.12 g/mol. IUPAC: (4Z)-4-[hydroxy(phenyl)methylidene]-1-(3-methylphenyl)-5-(2-nitrophenyl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one
Property Insights of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one
The XLogP value of 4.52952 indicates that 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 100.75 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The CAS number of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one is 337492-45-2.
What is the molecular formula of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one is C24H18N2O5.
What is the molecular weight of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one is 414.12 g/mol.
Where can I buy 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-benzoyl-3-hydroxy-5-(2-nitrophenyl)-1-(m-tolyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.