(3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one
TL;DR: (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one (CAS 337351-93-6) is a chemical compound with molecular formula C18H11BrN2O and molecular weight 350.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one
Also Known As: BAS 01258598, (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one, AJ-292/37042007, 5-Bromo-3-quinolin-2-ylmethylene-1,3-dihydro-indol-2-one, (Z)-5-bromo-3-(quinolin-2-ylmethylene)indolin-2-one
| Molecular Formula | C18H11BrN2O |
|---|---|
| Molecular Weight | 350.01 g/mol |
| LogP | 4.49 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 350.0055 |
| Heavy Atoms | 22 |
| Complexity | 946.725 |
Chemical Identifiers
| CAS Number | 337351-93-6 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=CC(=N2)/C=C\3/C4=C(C=CC(=C4)Br)NC3=O |
Product Overview
(3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one (CAS 337351-93-6), with molecular formula C18H11BrN2O and molecular weight 350.01 g/mol. IUPAC: (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one.
Chemical Property Profile of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one
Property Insights of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one
The XLogP value of 4.49 indicates that (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one?
The CAS number of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one is 337351-93-6.
What is the molecular formula of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one?
The molecular formula of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one is C18H11BrN2O.
What is the molecular weight of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one?
The molecular weight of (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one is 350.01 g/mol.
Where can I buy (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one?
You can request a quote for (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for (3Z)-5-bromo-3-(quinolin-2-ylmethylidene)-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.