N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide
TL;DR: N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide (CAS 33492-20-5) is a chemical compound with molecular formula C17H12F6N2O2 and molecular weight 390.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide
Also Known As: N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide, N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide, Biarylamide derivative, N1,N3-Bis(3-(trifluoromethyl)phenyl)malonamide, BIM-0015484.P001
| Molecular Formula | C17H12F6N2O2 |
|---|---|
| Molecular Weight | 390.08 g/mol |
| LogP | 5.0 |
| Topological Polar Surface Area | 58.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 4 |
| Exact Mass | 390.0803 |
| Heavy Atoms | 27 |
| Complexity | 488.0 |
Chemical Identifiers
| CAS Number | 33492-20-5 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=O)CC(=O)NC2=CC=CC(=C2)C(F)(F)F)C(F)(F)F |
| InChIKey | PLYOBKOGKORFMB-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide (CAS 33492-20-5), with molecular formula C17H12F6N2O2 and molecular weight 390.08 g/mol. IUPAC: N,N'-bis[3-(trifluoromethyl)phenyl]propanediamide.
Chemical Property Profile of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide
Property Insights of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide
The XLogP value of 5.0 indicates that N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.2 Ų, N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide?
The CAS number of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide is 33492-20-5.
What is the molecular formula of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide?
The molecular formula of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide is C17H12F6N2O2.
What is the molecular weight of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide?
The molecular weight of N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide is 390.08 g/mol.
Where can I buy N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide?
You can request a quote for N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide?
Yes, KEHONG BIO provides custom synthesis services for N,N'-Bis-(3-trifluoromethyl-phenyl)-malonamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.