4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline
TL;DR: 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline (CAS 33389-36-5) is a chemical compound with molecular formula C14H12N4O3S and molecular weight 316.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]ethanol
Also Known As: 4- -2- -QUINAZOLINE, 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline, 2-(2-(5-Nitro-2-thienyl)-4-quinazolinyl)aminoethanol, 2-((2-(5-Nitrothiophen-2-yl)quinazolin-4-yl)amino)ethanol, Quinazoline, 4-(2-hydroxyethylamino)-2-(5-nitro-2-thienyl)-
| Molecular Formula | C14H12N4O3S |
|---|---|
| Molecular Weight | 316.06 g/mol |
| LogP | 2.7 |
| Topological Polar Surface Area | 132.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 316.06302 |
| Heavy Atoms | 22 |
| Complexity | 395.0 |
Chemical Identifiers
| CAS Number | 33389-36-5 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(S3)[N+](=O)[O-])NCCO |
| InChIKey | QPLQHOGBXHYUEB-UHFFFAOYSA-N |
Product Overview
4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline (CAS 33389-36-5), with molecular formula C14H12N4O3S and molecular weight 316.06 g/mol. IUPAC: 2-[[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]ethanol.
Chemical Property Profile of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline
Property Insights of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline. The TPSA of 132.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline. Following Lipinski's Rule of Five, 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline?
The CAS number of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline is 33389-36-5.
What is the molecular formula of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline?
The molecular formula of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline is C14H12N4O3S.
What is the molecular weight of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline?
The molecular weight of 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline is 316.06 g/mol.
Where can I buy 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline?
You can request a quote for 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-(2-Hydroxyethylamino)-2-(5-nitro-2-thienyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.