Buspirone Hydrochloride structure

Buspirone Hydrochloride

TL;DR: Buspirone Hydrochloride (CAS 33386-08-2) is a chemical compound with molecular formula C21H32ClN5O2 and molecular weight 421.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride

Also Known As: Buspirone hydrochloride, Buspar, Buspirone HCL, Narol, buspirone

CAS: 33386-08-2
Molecular Formula C21H32ClN5O2
Molecular Weight 421.22 g/mol
LogP 2.51
Topological Polar Surface Area 69.6 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 6
Exact Mass 421.22446
Heavy Atoms 29
Complexity 529.0

Chemical Identifiers

CAS Number 33386-08-2
SMILES C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl
InChIKey RICLFGYGYQXUFH-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 10 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (12 patents) Analytical Reagents (26 patents) Biotechnology (67 patents) Catalysts (11 patents) Heterocyclic Building Blocks (59 patents) +5 more

Product Overview

Buspirone Hydrochloride (CAS 33386-08-2), with molecular formula C21H32ClN5O2 and molecular weight 421.22 g/mol. IUPAC: 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Buspirone Hydrochloride

XLogP
2.51
TPSA (Topological Polar Surface Area)
69.6
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
6
Heavy Atoms
29
Complexity
529.0
Exact Mass
421.22446
Monoisotopic Mass
421.22446
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Buspirone Hydrochloride

The XLogP value of 2.51 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Buspirone Hydrochloride. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Buspirone Hydrochloride. Following Lipinski's Rule of Five, Buspirone Hydrochloride has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Buspirone Hydrochloride?

The CAS number of Buspirone Hydrochloride is 33386-08-2.

What is the molecular formula of Buspirone Hydrochloride?

The molecular formula of Buspirone Hydrochloride is C21H32ClN5O2.

What is the molecular weight of Buspirone Hydrochloride?

The molecular weight of Buspirone Hydrochloride is 421.22 g/mol.

Where can I buy Buspirone Hydrochloride?

You can request a quote for Buspirone Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Buspirone Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Buspirone Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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