(E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one
TL;DR: (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one (CAS 333771-20-3) is a chemical compound with molecular formula C14H14N2O2S and molecular weight 274.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[(4-hydroxyphenyl)methylidene]-2-pyrrolidin-1-yl-1,3-thiazol-4-one
Also Known As: BAS 01053947, 5-(4-Hydroxy-benzylidene)-2-pyrrolidin-1-yl-thiazol-4-one, (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one, (5E)-5-[(4-hydroxyphenyl)methylidene]-2-pyrrolidin-1-yl-1,3-thiazol-4-one, (5E)-5-[(4-HYDROXYPHENYL)METHYLIDENE]-2-(PYRROLIDIN-1-YL)-4,5-DIHYDRO-1,3-THIAZOL-4-ONE
| Molecular Formula | C14H14N2O2S |
|---|---|
| Molecular Weight | 274.08 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 78.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 274.0776 |
| Heavy Atoms | 19 |
| Complexity | 419.0 |
Chemical Identifiers
| CAS Number | 333771-20-3 |
|---|---|
| SMILES | C1CCN(C1)C2=NC(=O)/C(=C\C3=CC=C(C=C3)O)/S2 |
| InChIKey | MXGUCOMZFKFPPN-FMIVXFBMSA-N |
Product Overview
(E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one (CAS 333771-20-3), with molecular formula C14H14N2O2S and molecular weight 274.08 g/mol. IUPAC: (5E)-5-[(4-hydroxyphenyl)methylidene]-2-pyrrolidin-1-yl-1,3-thiazol-4-one.
Chemical Property Profile of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one
Property Insights of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one. The TPSA of 78.2 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one. Following Lipinski's Rule of Five, (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one?
The CAS number of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one is 333771-20-3.
What is the molecular formula of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one?
The molecular formula of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one is C14H14N2O2S.
What is the molecular weight of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one?
The molecular weight of (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one is 274.08 g/mol.
Where can I buy (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one?
You can request a quote for (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-5-(4-hydroxybenzylidene)-2-(pyrrolidin-1-yl)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.