N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide
TL;DR: N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide (CAS 333768-49-3) is a chemical compound with molecular formula C17H16F3N3O and molecular weight 335.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide
Also Known As: N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide
| Molecular Formula | C17H16F3N3O |
|---|---|
| Molecular Weight | 335.12 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 35.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 335.12454 |
| Heavy Atoms | 24 |
| Complexity | 423.0 |
Chemical Identifiers
| CAS Number | 333768-49-3 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=C(C=C2)F)C(=O)NC3=C(C=C(C=C3)F)F |
| InChIKey | DQMKMIRYVOPKJY-UHFFFAOYSA-N |
Product Overview
N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide (CAS 333768-49-3), with molecular formula C17H16F3N3O and molecular weight 335.12 g/mol. IUPAC: N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide.
Chemical Property Profile of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide
Property Insights of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide
The XLogP value of 3.0 indicates that N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.6 Ų, N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide?
The CAS number of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide is 333768-49-3.
What is the molecular formula of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide?
The molecular formula of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide is C17H16F3N3O.
What is the molecular weight of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide?
The molecular weight of N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide is 335.12 g/mol.
Where can I buy N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide?
You can request a quote for N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-(2,4-difluorophenyl)-4-(4-fluorophenyl)piperazine-1-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.