![N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide structure](/static/products/3337/333768-47-1.webp)
N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
TL;DR: N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide (CAS 333768-47-1) is a chemical compound with molecular formula C18H18F3N3O and molecular weight 349.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
Also Known As: N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide, BAS 00944075, 4-(3-Trifluoromethyl-phenyl)-piperazine-1-carboxylic acid phenylamide, N-phenyl{4-[3-(trifluoromethyl)phenyl]piperazinyl}carboxamide, N-PHENYL(4-(3-(TRIFLUOROMETHYL)PHENYL)PIPERAZINYL)FORMAMIDE
| Molecular Formula | C18H18F3N3O |
|---|---|
| Molecular Weight | 349.14 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 35.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 349.1402 |
| Heavy Atoms | 25 |
| Complexity | 443.0 |
Chemical Identifiers
| CAS Number | 333768-47-1 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC(=C2)C(F)(F)F)C(=O)NC3=CC=CC=C3 |
| InChIKey | MFJDAIPRGRZEBQ-UHFFFAOYSA-N |
Product Overview
N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide (CAS 333768-47-1), with molecular formula C18H18F3N3O and molecular weight 349.14 g/mol. IUPAC: N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide.
Chemical Property Profile of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
Property Insights of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide
The XLogP value of 3.6 indicates that N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.6 Ų, N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide?
The CAS number of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide is 333768-47-1.
What is the molecular formula of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide?
The molecular formula of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide is C18H18F3N3O.
What is the molecular weight of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide?
The molecular weight of N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide is 349.14 g/mol.
Where can I buy N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide?
You can request a quote for N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for N-phenyl-4-[3-(trifluoromethyl)phenyl]piperazine-1-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.