4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline
TL;DR: 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline (CAS 33372-40-6) is a chemical compound with molecular formula C15H14N4O4S and molecular weight 346.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]propane-1,2-diol
Also Known As: PNTQ, 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline, 3-(2-(5-Nitro-2-thienyl)-4-quinazolinylamino)-1,2-propanediol, 3-((2-(5-Nitrothiophen-2-yl)quinazolin-4-yl)amino)propane-1,2-diol, Quinazoline, 4-(2,3-dihydroxypropylamino)-2-(5-nitro-2-thienyl)-
| Molecular Formula | C15H14N4O4S |
|---|---|
| Molecular Weight | 346.07 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 152.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 346.07358 |
| Heavy Atoms | 24 |
| Complexity | 438.0 |
Chemical Identifiers
| CAS Number | 33372-40-6 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(S3)[N+](=O)[O-])NCC(CO)O |
| InChIKey | PXASLEFBHWPUSR-UHFFFAOYSA-N |
Product Overview
4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline (CAS 33372-40-6), with molecular formula C15H14N4O4S and molecular weight 346.07 g/mol. IUPAC: 3-[[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]propane-1,2-diol.
Chemical Property Profile of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline
Property Insights of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline. The TPSA of 152.0 Ų indicates high polarity, suggesting 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline?
The CAS number of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline is 33372-40-6.
What is the molecular formula of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline?
The molecular formula of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline is C15H14N4O4S.
What is the molecular weight of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline?
The molecular weight of 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline is 346.07 g/mol.
Where can I buy 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline?
You can request a quote for 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.