4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline
TL;DR: 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline (CAS 33372-39-3) is a chemical compound with molecular formula C16H16N4O4S and molecular weight 360.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[2-hydroxyethyl-[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]ethanol
Also Known As: rac-2-propoxycyclohexanone, 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline, 4-BIS AMINO-2- QUINAZOLINE, 2,2'-(2-(5-Nitro-2-thienyl)-4-quinazolinyl)iminobis(ethanol), 2,2'-((2-(5-Nitrothiophen-2-yl)quinazolin-4-yl)azanediyl)diethanol
| Molecular Formula | C16H16N4O4S |
|---|---|
| Molecular Weight | 360.09 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 144.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 360.08923 |
| Heavy Atoms | 25 |
| Complexity | 446.0 |
Chemical Identifiers
| CAS Number | 33372-39-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(S3)[N+](=O)[O-])N(CCO)CCO |
| InChIKey | QPDGFLZXRKDMRL-UHFFFAOYSA-N |
Product Overview
4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline (CAS 33372-39-3), with molecular formula C16H16N4O4S and molecular weight 360.09 g/mol. IUPAC: 2-[2-hydroxyethyl-[2-(5-nitrothiophen-2-yl)quinazolin-4-yl]amino]ethanol.
Chemical Property Profile of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline
Property Insights of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline. The TPSA of 144.0 Ų indicates high polarity, suggesting 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline?
The CAS number of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline is 33372-39-3.
What is the molecular formula of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline?
The molecular formula of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline is C16H16N4O4S.
What is the molecular weight of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline?
The molecular weight of 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline is 360.09 g/mol.
Where can I buy 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline?
You can request a quote for 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Bis(2-hydroxyethyl)amino-2-(5-nitro-2-thienyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.