Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate structure

Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate

TL;DR: Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate (CAS 333359-12-9) is a chemical compound with molecular formula C21H18BrNO3S and molecular weight 443.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 4-(4-bromophenyl)-2-[(4-methylbenzoyl)amino]thiophene-3-carboxylate

Also Known As: BAS 00795916, ETHYL 4-(4-BROMOPHENYL)-2-(4-METHYLBENZAMIDO)THIOPHENE-3-CARBOXYLATE, ethyl 4-(4-bromophenyl)-2-[(4-methylbenzoyl)amino]thiophene-3-carboxylate, ethyl 4-(4-bromophenyl)-2-[(4-methylphenyl)carbonylamino]thiophene-3-carboxyla te, ethyl 4-(4-bromophenyl)-2-{[(4-methylphenyl)carbonyl]amino}thiophene-3-carboxylate

CAS: 333359-12-9
Molecular Formula C21H18BrNO3S
Molecular Weight 443.02 g/mol
LogP 5.91502
Topological Polar Surface Area 55.4 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 443.01907
Heavy Atoms 27
Complexity 962.09674

Chemical Identifiers

CAS Number 333359-12-9
SMILES CCOC(=O)C1=C(SC=C1C2=CC=C(C=C2)Br)NC(=O)C3=CC=C(C=C3)C

Product Overview

Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate (CAS 333359-12-9), with molecular formula C21H18BrNO3S and molecular weight 443.02 g/mol. IUPAC: ethyl 4-(4-bromophenyl)-2-[(4-methylbenzoyl)amino]thiophene-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate

XLogP
5.91502
TPSA (Topological Polar Surface Area)
55.4
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
27
Complexity
962.09674
Exact Mass
443.01907
Monoisotopic Mass
443.01907
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate

The XLogP value of 5.91502 indicates that Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate?

The CAS number of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate is 333359-12-9.

What is the molecular formula of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate?

The molecular formula of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate is C21H18BrNO3S.

What is the molecular weight of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate?

The molecular weight of Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate is 443.02 g/mol.

Where can I buy Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate?

You can request a quote for Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl 4-(4-bromophenyl)-2-(4-methylbenzamido)thiophene-3-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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