![1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine structure](/static/products/3328/332899-32-8.webp)
1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine
TL;DR: 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine (CAS 332899-32-8) is a chemical compound with molecular formula C18H18ClF3N2O2S and molecular weight 418.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(4-chlorophenyl)sulfonyl-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine
Also Known As: BAS 01376276, 1-[(4-chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine, AT-057/40719759, 1-(4-chlorophenyl)sulfonyl-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine, 1-(4-Chloro-benzenesulfonyl)-4-(4-trifluoromethyl-benzyl)-piperazine
| Molecular Formula | C18H18ClF3N2O2S |
|---|---|
| Molecular Weight | 418.07 g/mol |
| LogP | 3.8653 |
| Topological Polar Surface Area | 40.62 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 418.07297 |
| Heavy Atoms | 27 |
| Complexity | 876.31793 |
Chemical Identifiers
| CAS Number | 332899-32-8 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=C(C=C2)C(F)(F)F)S(=O)(=O)C3=CC=C(C=C3)Cl |
Product Overview
1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine (CAS 332899-32-8), with molecular formula C18H18ClF3N2O2S and molecular weight 418.07 g/mol. IUPAC: 1-(4-chlorophenyl)sulfonyl-4-[[4-(trifluoromethyl)phenyl]methyl]piperazine.
Chemical Property Profile of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine
Property Insights of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine
The XLogP value of 3.8653 indicates that 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.62 Ų, 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine?
The CAS number of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine is 332899-32-8.
What is the molecular formula of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine?
The molecular formula of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine is C18H18ClF3N2O2S.
What is the molecular weight of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine?
The molecular weight of 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine is 418.07 g/mol.
Where can I buy 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine?
You can request a quote for 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-[(4-Chlorophenyl)sulfonyl]-4-[4-(trifluoromethyl)benzyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.