AE-848/14138108
TL;DR: AE-848/14138108 (CAS 332857-01-9) is a chemical compound with molecular formula C14H11Cl2F3N4O and molecular weight 378.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide
Also Known As: AE-848/14138108, 5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide, 5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide, 5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]1,3-diaz aperhydroine-2-carboxamide
| Molecular Formula | C14H11Cl2F3N4O |
|---|---|
| Molecular Weight | 378.03 g/mol |
| LogP | 3.9491 |
| Topological Polar Surface Area | 72.94 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.0262 |
| Heavy Atoms | 24 |
| Complexity | 805.8026 |
Chemical Identifiers
| CAS Number | 332857-01-9 |
|---|---|
| SMILES | C1C(NC2=CC(=NN2C1C(F)(F)F)C(=O)N)C3=CC(=C(C=C3)Cl)Cl |
Product Overview
AE-848/14138108 (CAS 332857-01-9), with molecular formula C14H11Cl2F3N4O and molecular weight 378.03 g/mol. IUPAC: 5-(3,4-dichlorophenyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide.
Chemical Property Profile of AE-848/14138108
Property Insights of AE-848/14138108
The XLogP value of 3.9491 indicates that AE-848/14138108 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.94 Ų falls within the moderate polarity range, balancing permeability and solubility for AE-848/14138108. Following Lipinski's Rule of Five, AE-848/14138108 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AE-848/14138108?
The CAS number of AE-848/14138108 is 332857-01-9.
What is the molecular formula of AE-848/14138108?
The molecular formula of AE-848/14138108 is C14H11Cl2F3N4O.
What is the molecular weight of AE-848/14138108?
The molecular weight of AE-848/14138108 is 378.03 g/mol.
Where can I buy AE-848/14138108?
You can request a quote for AE-848/14138108 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AE-848/14138108?
Yes, KEHONG BIO provides custom synthesis services for AE-848/14138108 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.