(E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide
TL;DR: (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide (CAS 332374-48-8) is a chemical compound with molecular formula C16H11FN2O2 and molecular weight 282.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(4-fluorophenyl)methylideneamino]-1-benzofuran-2-carboxamide
Also Known As: BAS 01506453, (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide, N-[(E)-(4-fluorophenyl)methylideneamino]-1-benzofuran-2-carboxamide
| Molecular Formula | C16H11FN2O2 |
|---|---|
| Molecular Weight | 282.08 g/mol |
| LogP | 3.3358 |
| Topological Polar Surface Area | 54.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 282.08044 |
| Heavy Atoms | 21 |
| Complexity | 773.51483 |
Chemical Identifiers
| CAS Number | 332374-48-8 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=C(O2)C(=O)N/N=C/C3=CC=C(C=C3)F |
Product Overview
(E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide (CAS 332374-48-8), with molecular formula C16H11FN2O2 and molecular weight 282.08 g/mol. IUPAC: N-[(E)-(4-fluorophenyl)methylideneamino]-1-benzofuran-2-carboxamide.
Chemical Property Profile of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide
Property Insights of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide
The XLogP value of 3.3358 indicates that (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.6 Ų, (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide?
The CAS number of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide is 332374-48-8.
What is the molecular formula of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide?
The molecular formula of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide is C16H11FN2O2.
What is the molecular weight of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide?
The molecular weight of (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide is 282.08 g/mol.
Where can I buy (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide?
You can request a quote for (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(4-fluorobenzylidene)benzofuran-2-carbohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.