Aprindine Hydrochloride structure

Aprindine Hydrochloride

TL;DR: Aprindine Hydrochloride (CAS 33237-74-0) is a chemical compound with molecular formula C22H31ClN2 and molecular weight 358.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine;hydrochloride

Also Known As: aprindine hydrochloride, Aprindine HCl, Aspenon, Amidonal, Ritmusin

CAS: 33237-74-0
Molecular Formula C22H31ClN2
Molecular Weight 358.22 g/mol
LogP 4.81
Topological Polar Surface Area 6.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 8
Exact Mass 358.2176
Heavy Atoms 25
Complexity 332.0

Chemical Identifiers

CAS Number 33237-74-0
SMILES CCN(CC)CCCN(C1CC2=CC=CC=C2C1)C3=CC=CC=C3.Cl
InChIKey KIPFVRHNAAZJOD-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (1 patents) Heterocyclic Building Blocks (2 patents) Pharmaceutical Intermediates (175 patents)

Product Overview

Aprindine Hydrochloride (CAS 33237-74-0), with molecular formula C22H31ClN2 and molecular weight 358.22 g/mol. IUPAC: N'-(2,3-dihydro-1H-inden-2-yl)-N,N-diethyl-N'-phenylpropane-1,3-diamine;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Aprindine Hydrochloride

XLogP
4.81
TPSA (Topological Polar Surface Area)
6.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
8
Heavy Atoms
25
Complexity
332.0
Exact Mass
358.2176
Monoisotopic Mass
358.2176
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Aprindine Hydrochloride

The XLogP value of 4.81 indicates that Aprindine Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Aprindine Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Aprindine Hydrochloride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Aprindine Hydrochloride?

The CAS number of Aprindine Hydrochloride is 33237-74-0.

What is the molecular formula of Aprindine Hydrochloride?

The molecular formula of Aprindine Hydrochloride is C22H31ClN2.

What is the molecular weight of Aprindine Hydrochloride?

The molecular weight of Aprindine Hydrochloride is 358.22 g/mol.

Where can I buy Aprindine Hydrochloride?

You can request a quote for Aprindine Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Aprindine Hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for Aprindine Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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