Nicergolyn structure

Nicergolyn

TL;DR: Nicergolyn (CAS 33227-10-0) is a chemical compound with molecular formula C28H32BrN3O9 and molecular weight 633.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(6aR,9R,10aR)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridin-1-ium-3-carboxylate;(2R)-2,3,4-trihydroxy-4-oxobutanoate

Also Known As: Nicergolyn, Nicergoline tartrate, Vasospan, Sermion, Adavin

CAS: 33227-10-0
Molecular Formula C28H32BrN3O9
Molecular Weight 633.13 g/mol
LogP -0.1273
Topological Polar Surface Area 176.0 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 10
Rotatable Bonds 7
Exact Mass 633.1322
Heavy Atoms 41
Complexity 827.0

Chemical Identifiers

CAS Number 33227-10-0
SMILES CN1C[C@@H](C[C@@]2([C@H]1CC3=CN(C4=CC=CC2=C34)C)OC)COC(=O)C5=CC(=C[NH+]=C5)Br.[C@@H](C(C(=O)O)O)(C(=O)[O-])O
InChIKey HPTSPLOLRPLNPI-PPOPTZJYSA-N

Product Overview

Nicergolyn (CAS 33227-10-0), with molecular formula C28H32BrN3O9 and molecular weight 633.13 g/mol. IUPAC: [(6aR,9R,10aR)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinolin-9-yl]methyl 5-bromopyridin-1-ium-3-carboxylate;(2R)-2,3,4-trihydroxy-4-oxobutanoate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Nicergolyn

XLogP
-0.1273
TPSA (Topological Polar Surface Area)
176.0
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
10
Rotatable Bonds
7
Heavy Atoms
41
Complexity
827.0
Exact Mass
633.1322
Monoisotopic Mass
633.1322
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Nicergolyn

The XLogP value of -0.1273 indicates that Nicergolyn is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 176.0 Ų indicates high polarity, suggesting Nicergolyn may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nicergolyn has 4 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Nicergolyn?

The CAS number of Nicergolyn is 33227-10-0.

What is the molecular formula of Nicergolyn?

The molecular formula of Nicergolyn is C28H32BrN3O9.

What is the molecular weight of Nicergolyn?

The molecular weight of Nicergolyn is 633.13 g/mol.

Where can I buy Nicergolyn?

You can request a quote for Nicergolyn directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Nicergolyn?

Yes, KEHONG BIO provides custom synthesis services for Nicergolyn and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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