5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one
TL;DR: 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one (CAS 332109-72-5) is a chemical compound with molecular formula C18H14Cl2N2O3S and molecular weight 408.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5E)-5-[[5-(2,5-dichlorophenyl)furan-2-yl]methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one
Also Known As: Salor-int l469408-1ea, 5-((5-(2,5-Dichlorophenyl)furan-2-yl)methylene)-2-morpholinothiazol-4(5H)-one, 5-((5-(2,5-DI-CL-PH)-2-FURYL)METHYLENE)-2-(4-MORPHOLINYL)-1,3-THIAZOL-4(5H)-ONE, (E)-5-((5-(2,5-dichlorophenyl)furan-2-yl)methylene)-2-morpholinothiazol-4(5H)-one, (5E)-5-[[5-(2,5-dichlorophenyl)furan-2-yl]methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one
| Molecular Formula | C18H14Cl2N2O3S |
|---|---|
| Molecular Weight | 408.01 g/mol |
| LogP | 4.5559 |
| Topological Polar Surface Area | 55.04 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 408.01022 |
| Heavy Atoms | 26 |
| Complexity | 916.9101 |
Chemical Identifiers
| CAS Number | 332109-72-5 |
|---|---|
| SMILES | C1COCCN1C2=NC(=O)/C(=C\C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/S2 |
Product Overview
5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one (CAS 332109-72-5), with molecular formula C18H14Cl2N2O3S and molecular weight 408.01 g/mol. IUPAC: (5E)-5-[[5-(2,5-dichlorophenyl)furan-2-yl]methylidene]-2-morpholin-4-yl-1,3-thiazol-4-one.
Chemical Property Profile of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one
Property Insights of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one
The XLogP value of 4.5559 indicates that 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.04 Ų, 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one?
The CAS number of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one is 332109-72-5.
What is the molecular formula of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one?
The molecular formula of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one is C18H14Cl2N2O3S.
What is the molecular weight of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one?
The molecular weight of 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one is 408.01 g/mol.
Where can I buy 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one?
You can request a quote for 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-((5-(2,5-DI-CL-PH)-2-Furyl)methylene)-2-(4-morpholinyl)-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.