1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole
TL;DR: 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole (CAS 331819-78-4) is a chemical compound with molecular formula C19H14ClFN2S and molecular weight 356.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(3-chlorophenyl)-3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazole
Also Known As: BAS 00600348, 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole, 2-(3-chlorophenyl)-3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazole, 1-(3-Chloro-phenyl)-5-(4-fluoro-phenyl)-3-thiophen-2-yl-4,5-dihydro-1H-pyrazole, 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
| Molecular Formula | C19H14ClFN2S |
|---|---|
| Molecular Weight | 356.06 g/mol |
| LogP | 5.8963 |
| Topological Polar Surface Area | 15.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 356.05502 |
| Heavy Atoms | 24 |
| Complexity | 874.64716 |
Chemical Identifiers
| CAS Number | 331819-78-4 |
|---|---|
| SMILES | C1C(N(N=C1C2=CC=CS2)C3=CC(=CC=C3)Cl)C4=CC=C(C=C4)F |
Product Overview
1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole (CAS 331819-78-4), with molecular formula C19H14ClFN2S and molecular weight 356.06 g/mol. IUPAC: 2-(3-chlorophenyl)-3-(4-fluorophenyl)-5-thiophen-2-yl-3,4-dihydropyrazole.
Chemical Property Profile of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole
Property Insights of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole
The XLogP value of 5.8963 indicates that 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 15.6 Ų, 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole?
The CAS number of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole is 331819-78-4.
What is the molecular formula of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole?
The molecular formula of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole is C19H14ClFN2S.
What is the molecular weight of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole?
The molecular weight of 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole is 356.06 g/mol.
Where can I buy 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole?
You can request a quote for 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-chlorophenyl)-5-(4-fluorophenyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.