3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
TL;DR: 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one (CAS 331758-78-2) is a chemical compound with molecular formula C21H18N2O and molecular weight 314.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-methylphenyl)-2-phenyl-1,2-dihydroquinazolin-4-one
Also Known As: BAS 00583694, J3.435.496K, 2-Phenyl-3-p-tolyl-2,3-dihydro-1H-quinazolin-4-one, 2-phenyl-3-(p-tolyl)-2,3-dihydroquinazolin-4(1h)-one, 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
| Molecular Formula | C21H18N2O |
|---|---|
| Molecular Weight | 314.14 g/mol |
| LogP | 4.76612 |
| Topological Polar Surface Area | 32.34 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 314.1419 |
| Heavy Atoms | 24 |
| Complexity | 871.8553 |
Chemical Identifiers
| CAS Number | 331758-78-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(NC3=CC=CC=C3C2=O)C4=CC=CC=C4 |
Product Overview
3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one (CAS 331758-78-2), with molecular formula C21H18N2O and molecular weight 314.14 g/mol. IUPAC: 3-(4-methylphenyl)-2-phenyl-1,2-dihydroquinazolin-4-one.
Chemical Property Profile of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
Property Insights of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one
The XLogP value of 4.76612 indicates that 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.34 Ų, 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one?
The CAS number of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one is 331758-78-2.
What is the molecular formula of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one?
The molecular formula of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one is C21H18N2O.
What is the molecular weight of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one?
The molecular weight of 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one is 314.14 g/mol.
Where can I buy 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one?
You can request a quote for 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 3-(4-methylphenyl)-2-phenyl-2,3-dihydroquinazolin-4(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.