RefChem:497617
TL;DR: RefChem:497617 (CAS 331466-65-0) is a chemical compound with molecular formula C19H11ClF3N3OS2 and molecular weight 453.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-amino-N-(4-chlorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
Also Known As: KSC-230-157-1, 3-amino-N-(4-chlorophenyl)-6-(thiophen-2-yl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-(4-chlorophenyl)-6-(2-thienyl)-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide, 3-AMINO-N-(4-CHLOROPHENYL)-6-(2-THIENYL)-4-(TRIFLUOROMETHYL)THIENO(2,3-B)PYRIDINE-2-CARBOXAMIDE, 3-amino-N-(4-chlorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide
| Molecular Formula | C19H11ClF3N3OS2 |
|---|---|
| Molecular Weight | 453.00 g/mol |
| LogP | 6.5315 |
| Topological Polar Surface Area | 68.01 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 452.9984 |
| Heavy Atoms | 29 |
| Complexity | 1202.3906 |
Chemical Identifiers
| CAS Number | 331466-65-0 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NC3=C(C(=C2)C(F)(F)F)C(=C(S3)C(=O)NC4=CC=C(C=C4)Cl)N |
Product Overview
RefChem:497617 (CAS 331466-65-0), with molecular formula C19H11ClF3N3OS2 and molecular weight 453.00 g/mol. IUPAC: 3-amino-N-(4-chlorophenyl)-6-thiophen-2-yl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide.
Chemical Property Profile of RefChem:497617
Property Insights of RefChem:497617
The XLogP value of 6.5315 indicates that RefChem:497617 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 68.01 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:497617. Following Lipinski's Rule of Five, RefChem:497617 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:497617?
The CAS number of RefChem:497617 is 331466-65-0.
What is the molecular formula of RefChem:497617?
The molecular formula of RefChem:497617 is C19H11ClF3N3OS2.
What is the molecular weight of RefChem:497617?
The molecular weight of RefChem:497617 is 453.00 g/mol.
Where can I buy RefChem:497617?
You can request a quote for RefChem:497617 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:497617?
Yes, KEHONG BIO provides custom synthesis services for RefChem:497617 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.