NPD524 structure

NPD524

TL;DR: NPD524 (CAS 331463-54-8) is a chemical compound with molecular formula C24H29NO3 and molecular weight 379.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-(1-phenylcyclopentyl)methanone

Also Known As: NPD524, BAS 00335453, BIM-0014893.P001, (6,7-dimethoxy-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)(1-phenylcyclopentyl)methanone, 6,7-dimethoxy-1-methyl-2-[(1-phenylcyclopentyl)carbonyl]-1,2,3,4-tetrahydroisoquinoline

CAS: 331463-54-8
Molecular Formula C24H29NO3
Molecular Weight 379.21 g/mol
LogP 4.6615
Topological Polar Surface Area 38.77 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 379.21475
Heavy Atoms 28
Complexity 855.65405

Chemical Identifiers

CAS Number 331463-54-8
SMILES CC1C2=CC(=C(C=C2CCN1C(=O)C3(CCCC3)C4=CC=CC=C4)OC)OC

Product Overview

NPD524 (CAS 331463-54-8), with molecular formula C24H29NO3 and molecular weight 379.21 g/mol. IUPAC: (6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-(1-phenylcyclopentyl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of NPD524

XLogP
4.6615
TPSA (Topological Polar Surface Area)
38.77
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
28
Complexity
855.65405
Exact Mass
379.21475
Monoisotopic Mass
379.21475
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of NPD524

The XLogP value of 4.6615 indicates that NPD524 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 38.77 Ų, NPD524 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, NPD524 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of NPD524?

The CAS number of NPD524 is 331463-54-8.

What is the molecular formula of NPD524?

The molecular formula of NPD524 is C24H29NO3.

What is the molecular weight of NPD524?

The molecular weight of NPD524 is 379.21 g/mol.

Where can I buy NPD524?

You can request a quote for NPD524 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for NPD524?

Yes, KEHONG BIO provides custom synthesis services for NPD524 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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