![2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone structure](/static/products/3314/331444-75-8.webp)
2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone
TL;DR: 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone (CAS 331444-75-8) is a chemical compound with molecular formula C8H13F3N2O2 and molecular weight 226.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2,2-trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone
Also Known As: 2,2,2-trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone, 2-[4-(trifluoroacetyl)-1-piperazinyl]ethanol, 2,2,2-trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethan-1-one, 2,2,2-Trifluoro-1-(4-(2-hydroxyethyl)piperazin-1-yl)ethanone, 2,2,2-trifluoro-1-[4-(2-hydroxyethyl)piperazinyl]ethan-1-one
| Molecular Formula | C8H13F3N2O2 |
|---|---|
| Molecular Weight | 226.09 g/mol |
| LogP | -0.3148 |
| Topological Polar Surface Area | 43.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 226.09291 |
| Heavy Atoms | 15 |
| Complexity | 224.4169 |
Chemical Identifiers
| CAS Number | 331444-75-8 |
|---|---|
| SMILES | C1CN(CCN1CCO)C(=O)C(F)(F)F |
Product Overview
2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone (CAS 331444-75-8), with molecular formula C8H13F3N2O2 and molecular weight 226.09 g/mol. IUPAC: 2,2,2-trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone.
Chemical Property Profile of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone
Property Insights of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone
The XLogP value of -0.3148 indicates that 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 43.78 Ų, 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone?
The CAS number of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone is 331444-75-8.
What is the molecular formula of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone?
The molecular formula of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone is C8H13F3N2O2.
What is the molecular weight of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone?
The molecular weight of 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone is 226.09 g/mol.
Where can I buy 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone?
You can request a quote for 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone?
Yes, KEHONG BIO provides custom synthesis services for 2,2,2-Trifluoro-1-[4-(2-hydroxyethyl)piperazin-1-yl]ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.