2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one
TL;DR: 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one (CAS 330829-03-3) is a chemical compound with molecular formula C18H13N3OS and molecular weight 319.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4-one
Also Known As: 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one, 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4-one, AE-848/37390017, 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)-3,4-dihydroquinazolin-4-one, 3-(thiazol-2-yl)-2-(p-tolyl)quinazolin-4(3H)-one
| Molecular Formula | C18H13N3OS |
|---|---|
| Molecular Weight | 319.08 g/mol |
| LogP | 3.81762 |
| Topological Polar Surface Area | 47.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 319.07794 |
| Heavy Atoms | 23 |
| Complexity | 1034.2506 |
Chemical Identifiers
| CAS Number | 330829-03-3 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=O)N2C4=NC=CS4 |
Product Overview
2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one (CAS 330829-03-3), with molecular formula C18H13N3OS and molecular weight 319.08 g/mol. IUPAC: 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4-one.
Chemical Property Profile of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one
Property Insights of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one
The XLogP value of 3.81762 indicates that 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.78 Ų, 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one?
The CAS number of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one is 330829-03-3.
What is the molecular formula of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one?
The molecular formula of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one is C18H13N3OS.
What is the molecular weight of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one?
The molecular weight of 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one is 319.08 g/mol.
Where can I buy 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one?
You can request a quote for 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one?
Yes, KEHONG BIO provides custom synthesis services for 2-(4-methylphenyl)-3-(1,3-thiazol-2-yl)quinazolin-4(3H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.