Hedgehog IN-1 structure

Hedgehog IN-1

TL;DR: Hedgehog IN-1 (CAS 330796-24-2) is a chemical compound with molecular formula C23H15ClF4N4O2 and molecular weight 490.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]methyl]urea

Also Known As: Hedgehog IN-1, Hedgehog-IN-7d, Hedgehog Antagonist VIII, Hedgehog Antagonist VII, N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea

CAS: 330796-24-2
Molecular Formula C23H15ClF4N4O2
Molecular Weight 490.08 g/mol
LogP 5.5187
Topological Polar Surface Area 76.02 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 490.08197
Heavy Atoms 34
Complexity 1436.0975

Chemical Identifiers

CAS Number 330796-24-2
SMILES C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F

Product Overview

Hedgehog IN-1 (CAS 330796-24-2), with molecular formula C23H15ClF4N4O2 and molecular weight 490.08 g/mol. IUPAC: 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]methyl]urea.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Hedgehog IN-1

XLogP
5.5187
TPSA (Topological Polar Surface Area)
76.02
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
34
Complexity
1436.0975
Exact Mass
490.08197
Monoisotopic Mass
490.08197
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Hedgehog IN-1

The XLogP value of 5.5187 indicates that Hedgehog IN-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 76.02 Ų falls within the moderate polarity range, balancing permeability and solubility for Hedgehog IN-1. Following Lipinski's Rule of Five, Hedgehog IN-1 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Hedgehog IN-1?

The CAS number of Hedgehog IN-1 is 330796-24-2.

What is the molecular formula of Hedgehog IN-1?

The molecular formula of Hedgehog IN-1 is C23H15ClF4N4O2.

What is the molecular weight of Hedgehog IN-1?

The molecular weight of Hedgehog IN-1 is 490.08 g/mol.

Where can I buy Hedgehog IN-1?

You can request a quote for Hedgehog IN-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Hedgehog IN-1?

Yes, KEHONG BIO provides custom synthesis services for Hedgehog IN-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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