AF-399/13478006
TL;DR: AF-399/13478006 (CAS 330677-67-3) is a chemical compound with molecular formula C23H25N3OS and molecular weight 391.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
Also Known As: AF-399/13478006, F0164-0001, 1-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)-1,4,5,6,7,8-hexahydroquinazoline-4-thione, 1-(4-(dimethylamino)phenyl)-2-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinazoline-4(1H)-thione, 1-(4-dimethylaminophenyl)-2-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione
| Molecular Formula | C23H25N3OS |
|---|---|
| Molecular Weight | 391.17 g/mol |
| LogP | 5.22219 |
| Topological Polar Surface Area | 30.29 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 391.17184 |
| Heavy Atoms | 28 |
| Complexity | 1037.1829 |
Chemical Identifiers
| CAS Number | 330677-67-3 |
|---|---|
| SMILES | CN(C)C1=CC=C(C=C1)N2C3=C(CCCC3)C(=S)N=C2C4=CC=C(C=C4)OC |
Product Overview
AF-399/13478006 (CAS 330677-67-3), with molecular formula C23H25N3OS and molecular weight 391.17 g/mol. IUPAC: 1-[4-(dimethylamino)phenyl]-2-(4-methoxyphenyl)-5,6,7,8-tetrahydroquinazoline-4-thione.
Chemical Property Profile of AF-399/13478006
Property Insights of AF-399/13478006
The XLogP value of 5.22219 indicates that AF-399/13478006 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.29 Ų, AF-399/13478006 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/13478006 has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/13478006?
The CAS number of AF-399/13478006 is 330677-67-3.
What is the molecular formula of AF-399/13478006?
The molecular formula of AF-399/13478006 is C23H25N3OS.
What is the molecular weight of AF-399/13478006?
The molecular weight of AF-399/13478006 is 391.17 g/mol.
Where can I buy AF-399/13478006?
You can request a quote for AF-399/13478006 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/13478006?
Yes, KEHONG BIO provides custom synthesis services for AF-399/13478006 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.