Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate
TL;DR: Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate (CAS 330189-97-4) is a chemical compound with molecular formula C14H11F3N2O3S and molecular weight 344.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 2-[[3-(trifluoromethyl)benzoyl]amino]-1,3-thiazole-4-carboxylate
Also Known As: ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate, F0317-0265, ethyl 2-[[3-(trifluoromethyl)benzoyl]amino]-1,3-thiazole-4-carboxylate, ETHYL 2-[3-(TRIFLUOROMETHYL)BENZAMIDO]-1,3-THIAZOLE-4-CARBOXYLATE
| Molecular Formula | C14H11F3N2O3S |
|---|---|
| Molecular Weight | 344.04 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 96.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 344.04425 |
| Heavy Atoms | 23 |
| Complexity | 447.0 |
Chemical Identifiers
| CAS Number | 330189-97-4 |
|---|---|
| SMILES | CCOC(=O)C1=CSC(=N1)NC(=O)C2=CC(=CC=C2)C(F)(F)F |
| InChIKey | PQXRXRQTRBLGEL-UHFFFAOYSA-N |
Product Overview
Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate (CAS 330189-97-4), with molecular formula C14H11F3N2O3S and molecular weight 344.04 g/mol. IUPAC: ethyl 2-[[3-(trifluoromethyl)benzoyl]amino]-1,3-thiazole-4-carboxylate.
Chemical Property Profile of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate
Property Insights of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate
The XLogP value of 3.6 indicates that Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate. Following Lipinski's Rule of Five, Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate?
The CAS number of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate is 330189-97-4.
What is the molecular formula of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate?
The molecular formula of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate is C14H11F3N2O3S.
What is the molecular weight of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate?
The molecular weight of Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate is 344.04 g/mol.
Where can I buy Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate?
You can request a quote for Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for Ethyl 2-(3-(trifluoromethyl)benzamido)thiazole-4-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.