N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide
TL;DR: N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide (CAS 329920-70-9) is a chemical compound with molecular formula C12H6BrClF2N2O and molecular weight 345.93 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(5-bromo-2-pyridinyl)-2-chloro-4,5-difluorobenzamide
Also Known As: N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide, BIM-0008367.P001, N-(5-bromo-2-pyridinyl)-2-chloro-4,5-difluorobenzamide, N-(5-bromo(2-pyridyl))(2-chloro-4,5-difluorophenyl)carboxamide
| Molecular Formula | C12H6BrClF2N2O |
|---|---|
| Molecular Weight | 345.93 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 42.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 345.932 |
| Heavy Atoms | 19 |
| Complexity | 337.0 |
Chemical Identifiers
| CAS Number | 329920-70-9 |
|---|---|
| SMILES | C1=CC(=NC=C1Br)NC(=O)C2=CC(=C(C=C2Cl)F)F |
| InChIKey | OQLJBEDIGSSOOK-UHFFFAOYSA-N |
Product Overview
N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide (CAS 329920-70-9), with molecular formula C12H6BrClF2N2O and molecular weight 345.93 g/mol. IUPAC: N-(5-bromo-2-pyridinyl)-2-chloro-4,5-difluorobenzamide.
Chemical Property Profile of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide
Property Insights of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide
The XLogP value of 3.5 indicates that N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.0 Ų, N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide?
The CAS number of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide is 329920-70-9.
What is the molecular formula of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide?
The molecular formula of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide is C12H6BrClF2N2O.
What is the molecular weight of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide?
The molecular weight of N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide is 345.93 g/mol.
Where can I buy N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide?
You can request a quote for N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-bromopyridin-2-yl)-2-chloro-4,5-difluorobenzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.