Thioguanosine
TL;DR: Thioguanosine (CAS 32976-84-4) is a chemical compound with molecular formula C10H13N5O4S and molecular weight 299.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
Also Known As: 6-Thioguanosine, THIOGUANOSINE, Guanosine, 6-thio-, 6-Mercaptoguanosine, Ribosylthioguanine
| Molecular Formula | C10H13N5O4S |
|---|---|
| Molecular Weight | 299.07 g/mol |
| LogP | -1.31741 |
| Topological Polar Surface Area | 142.44 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 299.06882 |
| Heavy Atoms | 20 |
| Complexity | 700.50305 |
Chemical Identifiers
| CAS Number | 32976-84-4 |
|---|---|
| SMILES | C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)NC(=NC2=S)N |
Product Overview
Thioguanosine (CAS 32976-84-4), with molecular formula C10H13N5O4S and molecular weight 299.07 g/mol. IUPAC: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione.
Chemical Property Profile of Thioguanosine
Property Insights of Thioguanosine
The XLogP value of -1.31741 indicates that Thioguanosine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 142.44 Ų indicates high polarity, suggesting Thioguanosine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Thioguanosine has 5 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thioguanosine?
The CAS number of Thioguanosine is 32976-84-4.
What is the molecular formula of Thioguanosine?
The molecular formula of Thioguanosine is C10H13N5O4S.
What is the molecular weight of Thioguanosine?
The molecular weight of Thioguanosine is 299.07 g/mol.
Where can I buy Thioguanosine?
You can request a quote for Thioguanosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thioguanosine?
Yes, KEHONG BIO provides custom synthesis services for Thioguanosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.