AF-399/15286992
TL;DR: AF-399/15286992 (CAS 329225-45-8) is a chemical compound with molecular formula C26H22F3NO3 and molecular weight 453.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-hydroxy-3-naphthalen-1-yl-8-(piperidin-1-ylmethyl)-2-(trifluoromethyl)chromen-4-one
Also Known As: AF-399/15286992, 7-hydroxy-3-naphthalen-1-yl-8-(piperidin-1-ylmethyl)-2-(trifluoromethyl)chromen-4-one, 7-hydroxy-3-(1-naphthyl)-8-(1-piperidinylmethyl)-2-(trifluoromethyl)-4H-chromen-4-one, 7-hydroxy-3-(naphthalen-1-yl)-8-(piperidin-1-ylmethyl)-2-(trifluoromethyl)-4H-chromen-4-one, 7-hydroxy-3-naphthyl-8-(piperidylmethyl)-2-(trifluoromethyl)chromen-4-one
| Molecular Formula | C26H22F3NO3 |
|---|---|
| Molecular Weight | 453.16 g/mol |
| LogP | 6.3235 |
| Topological Polar Surface Area | 53.68 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 453.15518 |
| Heavy Atoms | 33 |
| Complexity | 1396.824 |
Chemical Identifiers
| CAS Number | 329225-45-8 |
|---|---|
| SMILES | C1CCN(CC1)CC2=C(C=CC3=C2OC(=C(C3=O)C4=CC=CC5=CC=CC=C54)C(F)(F)F)O |
Product Overview
AF-399/15286992 (CAS 329225-45-8), with molecular formula C26H22F3NO3 and molecular weight 453.16 g/mol. IUPAC: 7-hydroxy-3-naphthalen-1-yl-8-(piperidin-1-ylmethyl)-2-(trifluoromethyl)chromen-4-one.
Chemical Property Profile of AF-399/15286992
Property Insights of AF-399/15286992
The XLogP value of 6.3235 indicates that AF-399/15286992 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.68 Ų, AF-399/15286992 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/15286992 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15286992?
The CAS number of AF-399/15286992 is 329225-45-8.
What is the molecular formula of AF-399/15286992?
The molecular formula of AF-399/15286992 is C26H22F3NO3.
What is the molecular weight of AF-399/15286992?
The molecular weight of AF-399/15286992 is 453.16 g/mol.
Where can I buy AF-399/15286992?
You can request a quote for AF-399/15286992 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15286992?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15286992 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.