6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one
TL;DR: 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one (CAS 328947-69-9) is a chemical compound with molecular formula C12H9F5N2O and molecular weight 292.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one
Also Known As: 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one, 6-((2,2-difluoroethyl)amino)-4-(trifluoromethyl)quinolin-2(1h)-one
| Molecular Formula | C12H9F5N2O |
|---|---|
| Molecular Weight | 292.06 g/mol |
| LogP | 3.2239 |
| Topological Polar Surface Area | 44.89 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 292.0635 |
| Heavy Atoms | 20 |
| Complexity | 677.5825 |
Chemical Identifiers
| CAS Number | 328947-69-9 |
|---|---|
| SMILES | C1=CC2=C(C=C1NCC(F)F)C(=CC(=O)N2)C(F)(F)F |
Product Overview
6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one (CAS 328947-69-9), with molecular formula C12H9F5N2O and molecular weight 292.06 g/mol. IUPAC: 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one.
Chemical Property Profile of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one
Property Insights of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one
The XLogP value of 3.2239 indicates that 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.89 Ų, 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one?
The CAS number of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one is 328947-69-9.
What is the molecular formula of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one?
The molecular formula of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one is C12H9F5N2O.
What is the molecular weight of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one?
The molecular weight of 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one is 292.06 g/mol.
Where can I buy 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one?
You can request a quote for 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 6-(2,2-difluoroethylamino)-4-(trifluoromethyl)-1H-quinolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.