4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one
TL;DR: 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one (CAS 328947-55-3) is a chemical compound with molecular formula C13H13F3N2O and molecular weight 270.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(propylamino)-4-(trifluoromethyl)-1H-quinolin-2-one
Also Known As: J2.536.524K, 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one, 6-N-propyl -4-trifluoromethylquinolin-2(1H)-one, 6-propylamino-4-(trifluoromethyl)-1H-quinolin-2-one, 6-(propylamino)-4-(trifluoromethyl)-1,2-dihydroquinolin-2-one
| Molecular Formula | C13H13F3N2O |
|---|---|
| Molecular Weight | 270.10 g/mol |
| LogP | 3.3688 |
| Topological Polar Surface Area | 44.89 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 270.098 |
| Heavy Atoms | 19 |
| Complexity | 646.3589 |
Chemical Identifiers
| CAS Number | 328947-55-3 |
|---|---|
| SMILES | CCCNC1=CC2=C(C=C1)NC(=O)C=C2C(F)(F)F |
Product Overview
4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one (CAS 328947-55-3), with molecular formula C13H13F3N2O and molecular weight 270.10 g/mol. IUPAC: 6-(propylamino)-4-(trifluoromethyl)-1H-quinolin-2-one.
Chemical Property Profile of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one
Property Insights of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one
The XLogP value of 3.3688 indicates that 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.89 Ų, 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one?
The CAS number of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one is 328947-55-3.
What is the molecular formula of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one?
The molecular formula of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one is C13H13F3N2O.
What is the molecular weight of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one?
The molecular weight of 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one is 270.10 g/mol.
Where can I buy 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one?
You can request a quote for 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(Trifluoromethyl)-6-(propylamino)quinoline-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.