4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
TL;DR: 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine (CAS 328561-73-5) is a chemical compound with molecular formula C12H9F4N3O2 and molecular weight 303.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
Also Known As: 4-(2-fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine, BAS 00485813, 4-(2-fluorophenoxy)-6-(2,2,2-trifluoroethoxy)-2-pyrimidinamine, 4-(2-Fluoro-phenoxy)-6-(2,2,2-trifluoro-ethoxy)-pyrimidin-2-ylamine
| Molecular Formula | C12H9F4N3O2 |
|---|---|
| Molecular Weight | 303.06 g/mol |
| LogP | 2.9313 |
| Topological Polar Surface Area | 70.26 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 303.06308 |
| Heavy Atoms | 21 |
| Complexity | 634.1399 |
Chemical Identifiers
| CAS Number | 328561-73-5 |
|---|---|
| SMILES | C1=CC=C(C(=C1)OC2=NC(=NC(=C2)OCC(F)(F)F)N)F |
Product Overview
4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine (CAS 328561-73-5), with molecular formula C12H9F4N3O2 and molecular weight 303.06 g/mol. IUPAC: 4-(2-fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine.
Chemical Property Profile of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
Property Insights of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine
The XLogP value of 2.9313 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine. The TPSA of 70.26 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine. Following Lipinski's Rule of Five, 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine?
The CAS number of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine is 328561-73-5.
What is the molecular formula of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine?
The molecular formula of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine is C12H9F4N3O2.
What is the molecular weight of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine?
The molecular weight of 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine is 303.06 g/mol.
Where can I buy 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine?
You can request a quote for 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-(2-Fluorophenoxy)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.