4-Chloro-8-methylhydroquinoline-2-thione
TL;DR: 4-Chloro-8-methylhydroquinoline-2-thione (CAS 328288-80-8) is a chemical compound with molecular formula C10H8ClNS and molecular weight 209.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-8-methyl-1H-quinoline-2-thione
Also Known As: 4-Chloro-8-methylquinoline-2-thiol, 4-chloro-8-methylhydroquinoline-2-thione, 4-chloro-8-methylquinolin-2(1H)-thione, 4-chloro-8-methyl-1H-quinoline-2-thione, J1.713.249K
| Molecular Formula | C10H8ClNS |
|---|---|
| Molecular Weight | 209.01 g/mol |
| LogP | 2.6 |
| Topological Polar Surface Area | 44.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 209.00659 |
| Heavy Atoms | 13 |
| Complexity | 262.0 |
Chemical Identifiers
| CAS Number | 328288-80-8 |
|---|---|
| SMILES | CC1=C2C(=CC=C1)C(=CC(=S)N2)Cl |
| InChIKey | PXPFZXGRBAPJMR-UHFFFAOYSA-N |
Product Overview
4-Chloro-8-methylhydroquinoline-2-thione (CAS 328288-80-8), with molecular formula C10H8ClNS and molecular weight 209.01 g/mol. IUPAC: 4-chloro-8-methyl-1H-quinoline-2-thione.
Chemical Property Profile of 4-Chloro-8-methylhydroquinoline-2-thione
Property Insights of 4-Chloro-8-methylhydroquinoline-2-thione
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Chloro-8-methylhydroquinoline-2-thione. With a topological polar surface area (TPSA) of 44.1 Ų, 4-Chloro-8-methylhydroquinoline-2-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-8-methylhydroquinoline-2-thione has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-8-methylhydroquinoline-2-thione?
The CAS number of 4-Chloro-8-methylhydroquinoline-2-thione is 328288-80-8.
What is the molecular formula of 4-Chloro-8-methylhydroquinoline-2-thione?
The molecular formula of 4-Chloro-8-methylhydroquinoline-2-thione is C10H8ClNS.
What is the molecular weight of 4-Chloro-8-methylhydroquinoline-2-thione?
The molecular weight of 4-Chloro-8-methylhydroquinoline-2-thione is 209.01 g/mol.
Where can I buy 4-Chloro-8-methylhydroquinoline-2-thione?
You can request a quote for 4-Chloro-8-methylhydroquinoline-2-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-8-methylhydroquinoline-2-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-8-methylhydroquinoline-2-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.