![2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide structure](/static/products/3280/328036-06-2.webp)
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide
TL;DR: 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide (CAS 328036-06-2) is a chemical compound with molecular formula C16H11F2N3O2 and molecular weight 315.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-pyridin-3-ylprop-2-enamide
Also Known As: (E)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-pyridin-3-ylprop-2-enamide, 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide
| Molecular Formula | C16H11F2N3O2 |
|---|---|
| Molecular Weight | 315.08 g/mol |
| LogP | 3.22868 |
| Topological Polar Surface Area | 75.01 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 315.08194 |
| Heavy Atoms | 23 |
| Complexity | 738.1707 |
Chemical Identifiers
| CAS Number | 328036-06-2 |
|---|---|
| SMILES | C1=CC(=CN=C1)NC(=O)/C(=C/C2=CC=C(C=C2)OC(F)F)/C#N |
Product Overview
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide (CAS 328036-06-2), with molecular formula C16H11F2N3O2 and molecular weight 315.08 g/mol. IUPAC: (E)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-pyridin-3-ylprop-2-enamide.
Chemical Property Profile of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide
Property Insights of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide
The XLogP value of 3.22868 indicates that 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.01 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide. Following Lipinski's Rule of Five, 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide?
The CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide is 328036-06-2.
What is the molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide?
The molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide is C16H11F2N3O2.
What is the molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide?
The molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide is 315.08 g/mol.
Where can I buy 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide?
You can request a quote for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(pyridin-3-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.