![2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide structure](/static/products/3280/328030-34-8.webp)
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide
TL;DR: 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide (CAS 328030-34-8) is a chemical compound with molecular formula C19H16F2N2O5S and molecular weight 422.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(5-ethylsulfonyl-2-hydroxyphenyl)prop-2-enamide
Also Known As: 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide, (Z)-2-Cyano-3-[4-(difluoromethoxy)phenyl]-N-(5-ethylsulfonyl-2-hydroxyphenyl)prop-2-enamide
| Molecular Formula | C19H16F2N2O5S |
|---|---|
| Molecular Weight | 422.07 g/mol |
| LogP | 3.33288 |
| Topological Polar Surface Area | 116.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 422.0748 |
| Heavy Atoms | 29 |
| Complexity | 1074.7686 |
Chemical Identifiers
| CAS Number | 328030-34-8 |
|---|---|
| SMILES | CCS(=O)(=O)C1=CC(=C(C=C1)O)NC(=O)/C(=C\C2=CC=C(C=C2)OC(F)F)/C#N |
Product Overview
2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide (CAS 328030-34-8), with molecular formula C19H16F2N2O5S and molecular weight 422.07 g/mol. IUPAC: (Z)-2-cyano-3-[4-(difluoromethoxy)phenyl]-N-(5-ethylsulfonyl-2-hydroxyphenyl)prop-2-enamide.
Chemical Property Profile of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide
Property Insights of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide
The XLogP value of 3.33288 indicates that 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 116.49 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide. Following Lipinski's Rule of Five, 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide?
The CAS number of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide is 328030-34-8.
What is the molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide?
The molecular formula of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide is C19H16F2N2O5S.
What is the molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide?
The molecular weight of 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide is 422.07 g/mol.
Where can I buy 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide?
You can request a quote for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-3-[4-(difluoromethoxy)phenyl]-N-[5-(ethanesulfonyl)-2-hydroxyphenyl]prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.