(E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile
TL;DR: (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile (CAS 328029-52-3) is a chemical compound with molecular formula C19H11F3N2S and molecular weight 356.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-(4-phenyl-1,3-thiazol-2-yl)-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
Also Known As: (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile, (2E)-2-(4-phenyl-1,3-thiazol-2-yl)-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile, (E)-2-(4-phenyl-1,3-thiazol-2-yl)-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile
| Molecular Formula | C19H11F3N2S |
|---|---|
| Molecular Weight | 356.06 g/mol |
| LogP | 5.89308 |
| Topological Polar Surface Area | 36.68 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 356.0595 |
| Heavy Atoms | 25 |
| Complexity | 950.5457 |
Chemical Identifiers
| CAS Number | 328029-52-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CSC(=N2)/C(=C/C3=CC=CC=C3C(F)(F)F)/C#N |
Product Overview
(E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile (CAS 328029-52-3), with molecular formula C19H11F3N2S and molecular weight 356.06 g/mol. IUPAC: (E)-2-(4-phenyl-1,3-thiazol-2-yl)-3-[2-(trifluoromethyl)phenyl]prop-2-enenitrile.
Chemical Property Profile of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile
Property Insights of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile
The XLogP value of 5.89308 indicates that (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.68 Ų, (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile?
The CAS number of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile is 328029-52-3.
What is the molecular formula of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile?
The molecular formula of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile is C19H11F3N2S.
What is the molecular weight of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile?
The molecular weight of (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile is 356.06 g/mol.
Where can I buy (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile?
You can request a quote for (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-phenylthiazol-2-yl)-3-(2-(trifluoromethyl)phenyl)acrylonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.