(E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
TL;DR: (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide (CAS 327974-24-3) is a chemical compound with molecular formula C20H19ClN4O3S3 and molecular weight 494.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide
Also Known As: (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide, 2-({5-[(4-chlorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)-N'-[(E)-(2,3-dimethoxyphenyl)methylidene]acetohydrazide, 2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide, N-[(1E)-2-(2,3-dimethoxyphenyl)-1-azavinyl]-2-{5-[(4-chlorophenyl)methylthio]( 1,3,4-thiadiazol-2-ylthio)}acetamide
| Molecular Formula | C20H19ClN4O3S3 |
|---|---|
| Molecular Weight | 494.03 g/mol |
| LogP | 4.7434 |
| Topological Polar Surface Area | 85.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 494.0308 |
| Heavy Atoms | 31 |
| Complexity | 1044.4043 |
Chemical Identifiers
| CAS Number | 327974-24-3 |
|---|---|
| SMILES | COC1=CC=CC(=C1OC)/C=N/NC(=O)CSC2=NN=C(S2)SCC3=CC=C(C=C3)Cl |
Product Overview
(E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide (CAS 327974-24-3), with molecular formula C20H19ClN4O3S3 and molecular weight 494.03 g/mol. IUPAC: 2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-[(E)-(2,3-dimethoxyphenyl)methylideneamino]acetamide.
Chemical Property Profile of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
Property Insights of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide
The XLogP value of 4.7434 indicates that (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.7 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide. Following Lipinski's Rule of Five, (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The CAS number of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is 327974-24-3.
What is the molecular formula of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The molecular formula of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is C20H19ClN4O3S3.
What is the molecular weight of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
The molecular weight of (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide is 494.03 g/mol.
Where can I buy (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
You can request a quote for (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-((5-((4-chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N'-(2,3-dimethoxybenzylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.