1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid
TL;DR: 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid (CAS 327971-41-5) is a chemical compound with molecular formula C12H13F3N2O2 and molecular weight 274.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[5-(trifluoromethyl)-2-pyridinyl]piperidine-3-carboxylic acid
Also Known As: MixCom1_000292, Peakdale1_002954, 1-[5-(trifluoromethyl)pyridin-2-yl]piperidine-3-carboxylic acid, 1-[5-(Trifluoromethyl)pyridin-2-yl]piperidin-3-carboxylic acid, 1-(5-(trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid
| Molecular Formula | C12H13F3N2O2 |
|---|---|
| Molecular Weight | 274.09 g/mol |
| LogP | 2.4014 |
| Topological Polar Surface Area | 53.43 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 274.09293 |
| Heavy Atoms | 19 |
| Complexity | 459.03745 |
Chemical Identifiers
| CAS Number | 327971-41-5 |
|---|---|
| SMILES | C1CC(CN(C1)C2=NC=C(C=C2)C(F)(F)F)C(=O)O |
Product Overview
1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid (CAS 327971-41-5), with molecular formula C12H13F3N2O2 and molecular weight 274.09 g/mol. IUPAC: 1-[5-(trifluoromethyl)-2-pyridinyl]piperidine-3-carboxylic acid.
Chemical Property Profile of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid
Property Insights of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid
The XLogP value of 2.4014 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid. With a topological polar surface area (TPSA) of 53.43 Ų, 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid?
The CAS number of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid is 327971-41-5.
What is the molecular formula of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid?
The molecular formula of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid is C12H13F3N2O2.
What is the molecular weight of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid?
The molecular weight of 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid is 274.09 g/mol.
Where can I buy 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid?
You can request a quote for 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid?
Yes, KEHONG BIO provides custom synthesis services for 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidine-3-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.